Yes, you are right. Day ago after I understand, that it is not CP problem and found it.
00:30:20.379482 IP (tos 0x10, ttl 64, id 35366, offset 0, flags [DF], proto: TCP (6), length: 60) 31.173.230.232.10500 > 80.237.91.168.smtp: S, cksum 0x41a2 (correct), 3769254737:3769254737(0) win 5840 <mss 1460,sackOK,timestamp 634374519 0,nop,wscale 10>
00:30:20.507952 IP (tos 0x0, ttl 59, id 62007, offset 0, flags [none], proto: ICMP (1), length: 88) 80.237.91.168 > 31.173.230.232: ICMP host 80.237.91.168 unreachable - admin prohibited, length 68
So the problem on a remote side.