My opinion - say no to standalone setups with Check Point (unless it is not an SMB device).
Some time ago I implemented a setup of two 4800 appliances with increased RAM working in Full HA (FW + Mgmt) on R77.30 version of software. As I remember, some NGFW blades were enabled - IPS and Application Control. Something around 50 - 100 rules and standard profiles without much tuning.
Every time when policy was installed there were drops of traffic (very short, but visible with simple ping), because policy verification and compilation is quite a resource-demanding operation. The setup ended up with node 1 acting as active FW and node 2 as active management server. Not enough space on HDD to store logs for a longer time, log Indexing (SmartLog) was not really possible.
It also adds complexity to software upgrades and maintenance. Higher risks of ruining management database. Higher risks of some security issues. More time and troubles to restore a gateway from a backup. Snapshots might be not possible to make because there would be no enough space.
Of course, if there are much more powerful appliances you can try the setup. It would be interesting to know how it would perform, just for fun. But I think that anyone who buys some 15000-23000 appliances already has a server, most probably even MDS. Right?
And I would definitely not recommend standalone setup with R80.10 - management server will eat all RAM and CPU that you have. Although, there is this sk120131 which assumes that everything would be fine.