Moving this to Scalable Platforms
I assume you're using some sort of Active/Active configuration.
First of all, it depends on what appliances you have if this is even an option.
I believe Maestro requires 10GB (or higher) connectivity through a DAC, which definitely limits you to the 5600 and above.
That said, I have not seen anything official that says you can use the 5600/5800/5900 for Maestro, only the newer 6500/6800 and the 23000 series.
Second, it depends on the nature of the CPU/RAM loading.
If it is caused due to excessive sync, it will definitely help since you won't be incurring the sync overhead.
This also leads to better throughput.