Thanks Phoneboy. We created a chained exclusion for example of Box.exe, as well as a number of other Box processes that we found running. We used the format like so below:
We also tried making one that was wildcarded into the path. We don't get any logs indicating things are being blocked, so we're not sure what other process we might need. I presume this wildcard makes it recursive, but not sure.
OneDrive we also tested and it initially seemed to be working fine, then eventually generated an error. However, the files were all still accessible so that's acceptable as a fallback plan.