The best way to as an ISP is ensure your customers do not get blacklisted is very simple: Make sure you have an easy way for Internet users to report abuse emanating from your netblocks, AND ACTUALLY BE RESPONSIVE TO COMPLAINTS. Ensure that the abuse email addresses displayed with the WHOIS records associated with your domains & IP netblock allocations at ARIN/RIPE/APNIC/LACNIC/etc. are correct, and not filtered for anti-spam and attachments. Nothing is more infuriating than taking the time to file an abuse report only to have it bounce back because it was classified as spam, or the abuse mailbox is full, or it doesn't exist at all. It is also a great idea for users to be able to report abuse through a form on your main website, just make sure it is relatively easy to find.
Failing to do these things will ensure that the blacklists enforced against a single customer of yours will grow over time to include all netblocks assigned to the entire ISP, and catch your innocent customers in the collateral damage. Getting your netblocks extricated from dozens of Internet blacklists after the fact will be difficult if not impossible.
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