Thanks Phoneboy. We created a chained exclusion for example of Box.exe, as well as a number of other Box processes that we found running. We used the format like so below:
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We also tried making one that was wildcarded into the path. We don't get any logs indicating things are being blocked, so we're not sure what other process we might need. I presume this wildcard makes it recursive, but not sure.
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OneDrive we also tested and it initially seemed to be working fine, then eventually generated an error. However, the files were all still accessible so that's acceptable as a fallback plan.