In theory you could safely disable that signature, but in the real world there are many cases in which it would not be that safe.
In the future someone might add a secondary server of the same type and not patch it right away.
Or you might confuse that signature with a new one which prevents an unpatched vulnerability.
Also, the patch might not work correctly and the signature will probably be updated before you install the new patch.
While CPU is not an issue, I believe it is better to enable all recent protections to your servers. It makes it much easier to manage and leaves you some spare time to focus on disabling features you actually don't have in your network.