Yes Optimized is always a good profile to start with. Another strong recommendation is to create Global Exceptions as opposed to rule-based exceptions to facilitate the transition to Autonomous Threat Prevention should you want to go there in the future. When exceptions are created directly from the log card of a Threat Prevention log they are always created as rule-based exceptions. Found out the hard way that if you enable Autonomous Threat Prevention (ATP), rule-based exceptions suddenly stop working and only Global Exceptions apply. Really should be some kind of warning about this when enabling ATP if rule-based exceptions are present.
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