See sk65264: What is Jumbo frame and MTU Maximum length:
jumbo frame MTU range is 1500-16,000
But this is depending on IF, see details in sk170533: "Failed to set MTU [XXXX] on interface" error and find the remark:
it is generally not recommended to set an MTU size of more than 9000
So 4500 should be possible if supported by the IFs used on the way to the internet. But best practice is to make MTU larger only in small steps until the issue is resolved.
CCSP - CCSE / CCTE / CTPS / CCME / CCSM Elite / SMB Specialist