Long time lurker - just spent the last few hours with TAC on a very similar issue. I now feel obligated to share the result.
Upgraded from r80.30 to r80.10. Applied latest jhf (45). After successful upgrade, received generic error about an internal error when logging in to SmartConsole.
Services up, applied a not yet public sk178807 fix, handful of other things, still no luck.
The issue was with the Security Management GUI Clients defined. I personally had three entries; one specific IP, network range 0.0.0.0-0.0.0.0, and "any." My host met two of the three client types defined, only has to match one to be allowed to authenticate. And to remind you, did not have issues prior to upgrade.
We removed the single IP, and network range to just keep the "any" entry. BAM let me in.
BUG will be posted soon.. my scenario may not match yours exactly.. but it sure is close.. Just one stranger trying to help another.