I had done this probably 100 times and never had a single issue. In some RARE cases, which I had never encountered in all my years doing this is that say if there isn a problem with mgmt and CRL does not work within 24 hours, thats only issue I ever heard of, but personally, I never had that problem and its probably less than 1% chance that would happen.
One thing I would be aware of is that if you have mgmt with lots of space, it could take 2-3 hours to do FULL upgrade, as once it reboots, it would tell you its re "importing" the database over, but thats totally normal.
Other than that, I cant think of anything else that would be an issue.
Best,
Andy