As @Vincent_Bacher that command would simply change cluster state. It never needs a reboot, just make sure when you run clusterXL_admin down to run clusterXL_admin up right after, as that would change the state to standby.
Now, as far as your question for the different hotfixes, yes, absolutely, as long as mgmt server is same OR higher than gateways it manages, hotfix version is irrelevant, though for consistency, its best to keep them all on same jumbo.
Best regards,
Andy
Best,
Andy
"Have a great day and if its not, change it"