I'm not familiar with the terms "static" and "dynamic" being used to describe IPS Protections/Signatures. Perhaps you are referring to IPS ThreatCloud Protections which can be dynamically updated from the Check Point ThreatCloud, while IPS Core Protections and Inspection Settings (formerly part of IPS but now part of the Access Policy in R80.10+) are "static", ship with the product as-is, and cannot be updated from the ThreatCloud?
As far as your profile question, it depends on the version of the gateway. R77.30 and earlier gateways could only have one IPS Profile applied to traffic that was configured on the gateway object itself as the Protected Scope. R80.10+ gateways can have multiple IPS Profiles applied to different types of traffic via rules in the Threat Prevention policy.
Attend my online "Be your Own TAC: Part Deux" CheckMates event
March 27th with sessions for both the EMEA and Americas time zones